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Home Biotechnologies Antithrombotic calixarenes

Antithrombotic calixarenes


Calixarenes C-192 and C-145 that are inhibitors of blood coagulation due to inhibition of fibrin polymerization and the formation of thrombus fibrin network has been created. They can be use for treatment each of coagulation abnormalities, that accompanied by abnormal activation of blood coagulation system and which lead to blood clots formation in blood vessels: myocardial infarction, cerebrovascular strokes, ischemic heart disease, venous thromboembolism, disseminated intravascular coagulation, ischemic stroke, cancer, diabetes, and also for postoperative prophylaxis.

Innovative Aspect and Main Advantages

  • highly specific in action;
  • highly аntithrombotic activity;
  • effective in small doses;
  • cheap in manufacturing;
  • medium toxicity.

Areas of Application

Medicine (as antithrombotic drugs)

Antithrombotic calixarenes

Contact Details

Koshel T.A.
Organization: Palladin Institute of Biochemistry of NASU
Adress: 9, Leontovicha str., 01601, Kyiv, Ukraine
(+380 44) 2355172
This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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