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Home Biotechnologies Immunodiagnostic test systems for quantification of fibrinogen in human blood plasma

Immunodiagnostic test systems for quantification of fibrinogen in human blood plasma

Description

On the basis of obtained fibrinogen-specific mAbs test system for quantification of fibrinogen in human blood plasma has been developed. Fibrinogen (F) is the central protein of the blood coagulation system and soluble precursor of fibrin polymer forming the framework of a thrombus. Fibrinogen promotes aggregation of platelet by interacting with them. It is the first stage in the formation of the hemostatic plug platelet. Fibrinogen is acute phase protein and important marker of inflammation and necrosis of tissue. The causes of fibrinogen increasing: cardiovascular diseases, inflammation, trauma, malignant tumors, virulent disease and other pathologies.

Innovative Aspect and Main Advantages

  • The sensitivity of the testsystem: .......................... 1 ± 0,2 μg/ml;
  • The specificity of the testsystem: .......................... 98%;
  • The speed of the testsystem: ................................ 3 hours;
  • The test system has not analogues in Ukraine and CIS countries.

Areas of Application

Medicine



Contact Details

Olena Petrivna Kozulina
Organization: Palladin Institute of Biochemistry of NASU; “DiaprophMed”
Adress: 9, Leontovicha str., 01601, Kyiv, Ukraine
(+380 44) 2357157
This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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