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Home Biotechnologies Immunodiagnostic test systems for quantification of D-dimer in human blood plasma

Immunodiagnostic test systems for quantification of D-dimer in human blood plasma

Description

On the basis of obtained DD-specific mAbs test system for quantification of DD in human blood plasma has been developed.

The test system has not analogues in Ukraine and CIS countries. D-dimer (DD) is one of the main markers of thrombosis and fibrinolysis. DD is the largest molecular fragment of fibrin polymer degradation by plasmin stabilized by factor XIIIa. The causes of DD increasing: deep-vein thrombosis, pulmonary embolism, myocardial infarction, coronary heart disease, DIC, fibrinolytic and thrombolytic therapy, cancer; surgery, age is over 60 years, pregnancy. DD concentration below 500ng/ml allows 98% eliminating of pulmonary embolism and deepvein thrombosis.

Innovative Aspect and Main Advantages

  • The sensitivity of the method: ......................... 30 ± 6 ng/ml;
  • The specificity of the method: ......................... 98%;
  • The speed of the method: ............................... 3 hours;
  • The test system has not analogues in Ukraine and CIS countries.

Areas of Application

Medicine.



Contact Details

Olena Petrivna Kozulina
Organization: Palladin Institute of Biochemistry of NASU; “DiaprophMed”
Adress: 9, Leontovicha str., 01601, Kyiv, Ukraine
(+380 44) 2357157
This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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