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Home Biotechnologies Piezoelectric Nano-Manipulator PSF-3 For Cells Technologies

Piezoelectric Nano-Manipulator PSF-3 For Cells Technologies

To see additional piezoelectric technology click here
To see Youtube demo's click here or do Youtube search for "DTI Piezoelectric Valves"


The PSF-3 nano-manipulator works by converting the rotary motion of an advanced piezoelectric motor (fitted onto each axis of the nano-manipulator) into linear motion. A combination of high torque, variable speed and high angular resolution enables the piezoelectric motor to be used in either continuous or stepper mode. These characteristics facilitate a smooth transition, without degradation in intrinsic performance, from an angular step of less than 5 μrad to continuous motion, and a range of angular velocities, from 4 μrad/sec up to 60 rev/min. This translates into a linear resolution of 0.4 nm and a linear range of velocities from 0.5 nm/sec to 500 μm/sec for each axis of the PSF-3. Additional benefits of the PSF-3 design include the elimination of heat dissipation, ultra-low electrical noise and low supply voltage (12 VDC), which together make the PSF-3 ideal for very sensitive applications (e.g. delicate electrophysiological recordings).

Innovative Aspect and Main Advantages

LILEYA‘s PSF-3 is a state of the art 3-axis nano-manipulator system (fig.1), whose combination of extremely high resolution (0.4 nm), long term stability (drift less than 2 nm/hour @20°C) and long travel (10 mm) is unprecedented in the field. At the heart of the design is an advanced piezoelectric rotary motor PM-20R ( ), programmable joystick controller (fig.2). When the motor is deenergized, it provides an automatic solid brake on movement, with almost undetectable backlash and drift. The design of the PSF-3 makes it ideal for a variety of biomedical, microelectronic and optical applications.

Technical data for PSF-3 Nano-manipulator

  • Travel Range –––––––––––––––––––––––––––––––– 10 mm
  • Min. Linear Increment ––––––––––––––––––––––––– 0.4 nm
  • Long-term Drift –––––––––––––––––––––––––––––– <2 nm per hour @20°C
  • Velocity Range (Stepped – Continuous) –––––––––– (0.5 nm/sec to 500 μm/sec)
  • Max. Load – Capacity ––––––––––––––––––––––––– 3 kg
  • Supply Voltage –––––––––––––––––––––––––––––– 12 V
  • Nominal Power Consumption ––––––––––––––––––– 1 W
  • Maximum Power Consumption (per axis) ––––––––– 4 W
  • Dimensions (mm) –––––––––––––––––––––––––––– 208 (h) x 140 (w) x 110 (d)
  • Weight PSF-3/Joystick controller –––––––––––––––– 1.5 kg/0.5 kg

Areas of Application

LILEYA’s advanced Nano-Manipulator technology is designed to meet a variety of positioning needs for the scientific, biotechnology, medical, semiconductor and industrial markets.

It is suitable for applications such as:

  • patch clamp experiments on cells in culture,
  • microinjection into cells,
  • cell imaging,
  • cellular and material handling,
  • IVF fertilization and sterility treatments,
  • DNA cloning experiments,
  • extra cellular recording,
  • intracellular recording,
  • cytopathology,
  • precision robotic applications,
  • MRI-guided robotic surgery applications,
  • integrated circuits applications,
  • IC mask generation and alignment,
  • IC lithography,
  • IC wafer measurements,
  • fiber optic assembly and alignment,
  • laser production,
  • E-beam control for IC’s,
  • ion beam control for IC’s,
  • read-write heads for recording tape and CD’s,
  • storage media applications.

Fig. 1 Piezoelectric Nano-Manipulator PSF-3

Fig. 2 Joystick controller

Stage of Development

LILEYA’s unique designs are protected by:

  • United States Patent MICROMANIPULATOR , Application Serial No.#2005/0023930
  • Canadian Patent Application MICROMANIPULATOR, number 2527502
  • Russia Patent MICROMANIPULATOR No.2041480
  • UA Patent MICROMANIPULATOR No.2002064866

LILEYA builds systems with superior high performance characteristics and it can produce 100-400 systems per year

Contact Details

Dr. Sergii Petrenko, Director
Organization: Small Scientific Production Enterprise "LILEYA'ltd
Address: Kiev-02002, 3G Lunacharskogo str.
Tel/Fax: (380-44) 580-1376, Mob.: 8(067) 918-32-68
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