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Home Biotechnologies Polyfunctional surface-active regulator “polycom” for biomedicine and agriculture

Polyfunctional surface-active regulator “polycom” for biomedicine and agriculture

Description

New complex surface-active preparation “Polycom” of natural origin is developed. The preparation is highly-efficient, non-toxic, completely biodegradable, and able to substitute a range of synthetic analogues in modern technologies. The most valuable properties of “Polycom”:

  • emulsifying and demulsifying ability
  • moistening ability
  • environmentally safe
  • antimicrobial activity
  • ability of chemical modification

Biopreparation is polyfunctional regulator of membrane processes, influences on the permeability of cell membranes, executes transfer functions, promotes an activation of enzymes and other biologically-active substances.

Such properties are very important for use of biopreparation in biomedical technologies, pharmaceutical, food industry and in agriculture. The ability of reducing a concentration of active substances via including surface-active preparation into pharmacological compositions: ointments, creams, gels, shampoos etc., is determined. One of examples of application of biopreparation “Polycom” in pharmacy – the development of new medical form of complex antifungal mean based on purely soluble thiosulfanate and biosurfactant.

The cоntent of “Polycom”: efficient surfactants of glуcolipid origin with “soft” action and biopolymer, which together create a unique composition with surface-active and emulsifying properties. It is capable of causing a considerable decrease surface and interfacial tensions to values of 29.0 and 0.1-0.2 mN/m respectively and of forming stable highly dispersed emulsions (oils, hydrocarbons).

The product “Polycom” is obtained via controlled microbial synthesis based on natural substrates, its content and form of production can be modified depending on its application.

Innovative Aspect and Main Advantages

  • Universal emulsifier (solubilizer) of natural origin for different substances, works at the wide range of pH;
  • Regulator of activity of biologically-active substances (enzymes, biocides, growth stimulators etc. - increases of catalase enzyme activity in 3-4 times);
  • Regulator of processes of transfer of biologically-active substances into cell;
  • Ecologically safe modifier of surfaces of different type (alteration of hydrophobic-hydrophylic properties);

Such properties of biopreparation promote an improvement of existing and creation of new biomedical technologies. Preparations have specific advantages if compared with synthetic analogues: they are biodegradable, non-toxic, effective in extreme temperatures, pH, concentrations of salts. Their synthesis can be based on cheap substrates, including industrial waste products.

Areas of Application

Biomedical technologies: direct transport of biologically-active substances and other medical preparations in living organism; emulsification, moisturizing.

Ecologically safe cosmetic and hygienic means.

Pharmaceutical industry, cattle breeding: regulators of activity of enzyme and other biologically-active preparations. Means of plant nutrition and protection (biological control).

Food industry. This product will be of interest to companies typically working in the areas of biotechnology, biomedicine, pharmaceuticals, agriculture and food products.

Surface-active biopreparation “Polycom”.
Fig. 1 Surface-active bio-
preparation “Polycom”.

Scheme of transfer of biologically-active substances
Fig. 2 Scheme of transfer of biologically-active
substances (BAS) into cell using
biosurfactants (Biosur)

Influence of biopreparation “Polycom” (Biosur) on catalase enzyme activity.
Fig. 3 Influence of biopreparation “Polycom” (Biosur)
on catalase enzyme activity.

Stage of Development

Standard specifications of production are developed, sanitation certificate is obtained, pilot lots are obtained on experimental plants. The biopreparation “Polycom” is patented. Prototype is available for testing. The biopreparation is tested in laboratory.

Contact Details

Lviv Department of Physical Chemistry of Combustible Miner-als of L.M.Litvinenko Institute of Physical Organic Chemistry, National Academy of Sciences of Ukraine
Elena Karpenko, Ph.D., Head of Biotechnology Laboratory
Naukova Str., 3a, Lviv, 79053, Ukraine
Phone: (380 322) 63-51-74
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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