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Home Biotechnologies Tomography system for molecular imaging based on cylindrical scintillar

Tomography system for molecular imaging based on cylindrical scintillar


The visualization system, consisting of a cylindrical scintillation detector and parallelhole collimator rotating inside it, is the basis of the offered single-photon emission tomograph.

Such combination has several advantages over systems on the rotating head basis. First, the stationery position relative to each other during the testing allows obtaining the high spatial resolution of the whole system due to the exclusion of the image jitter because of the detection head inaccurate position as in the case with rotating heads.

The other factor which allows obtaining the high resolution is the solid collimator which excludes the possibility of the relative shift of the object projections from the specified position. So, the tomographic reconstruction artifacts, which are peculiar to gamma cameras with separate detectors, revealing themselves as specific image jitters when a point is transformed to a circle, are avoided.

In the offered system the research object is surrounded by three collimator sections, that lets obtain three tomographic projections simultaneously and to decrease the general time of the research in comparison with usual two-detector cameras. Besides in this configuration a collimator is situated practically on the minimal distance from the research object, due to it the high spatial resolution is obtained along the whole detector filed of view.

In conclusion the high reliability of such system, connected with the minimal quantity of rotating elements, which don’t carry any electronics, should be mentioned.

Innovative Aspect and Main Advantages

  • Cylindrical scintillation crystal.
  • No image artifacts.
  • Intrinsic resolution – not less than 4 mm.
  • Resolution of the reconstructed image – 5 mm.
  • Duration of one tomographic study – about 20 min.
  • High reliability

Areas of Application

  • Single photon emission tomograph for brain study
  • Mammo-SPECT systems
  • Tomographic systems for pharmacological studies of the small animals

Tomography system for molecular imaging based on cylindrical scintillar
Fig. 1 General view of the system.

Stage of Development

Single-photon tomography system for brain researches (OFECT-3) has gone through the medical testing and is ready for the production. In present time we are working on modification of some parts, connected with the unification of separate blocks of gamma-cameras produced by us.

Besides we are working on the creation of two-detector whole body gamma camera, which is going to replace OFECT-1 camera. This elaboration is carried out according to a module principle new for our practice. In gamma camera construction a lot of standard blocks, produced in the USA and EU countries, are applied. So we will replace the most problematic blocks for Ukrainian industry by the products of worldwide leaders working in this field and in this way we hope to get a ready product meeting the international requirements and competitive not only on the Ukrainian market. Medical testing of the new system is scheduled on May 2007.

Contact Details

Institute for scintillation materials NAS of Ukraine Vyacheslav Pedash
Lenin av. 60, Kharkov, Ukraine, 61001
Tel: +38057 3410172
Fax: +38057 3404474
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


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