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Home Biotechnologies Bacteriostatic Membranes

Bacteriostatic Membranes


The research deals with the development of polymeric membranes with bacteriostatic properties. To obtain bacteriostatic membranes two approaches will be used:
i) chemical modification of polymeric membranes;
ii) membrane formation using bacteriostatic fillers and additions introduced in polymer matrix.

Obtaining membranes with bacteriostatic activity are directed on the development of reverse osmosis (RO), nanofiltration (NF), ultrafiltration (UF) membranes as well as microfilters (MF). On the Kharkov heavy ion linear accelerator MILAC experimental investigations on irradiation polymer films with heavy ion beams are carried out with the aim of obtaining track-etched membranes. In the MILAC prestripping section triple-charge Ar403+ ions were accelerated to the energy of 1 MeV/u; PETF films 6~10 μm thick were irradiated, and after subsequent physical and chemical treatment it was possible to obtain experimental samples of track-etched membranes with through pores from 2 to 0.05 μm in diameter.

Innovative Aspect and Main Advantages

Aapproaches and methodology for giving bacteriostatic properties to polymeric membranes are new and unique in membranology.

The method of introducing such substances as chitosane, polyhexamethileneguanidine chloride (PHMG), quaternary ammonium salt and Ag nanoparticles in polymer solution has been developed. Method of grafting chitosane, quinolone, PHMG, iodine complex with polyvinylpyrrolidone, Ag nanoparticles to the surfaces of cellulose, acetate cellulose, polysulfone and polyethylentereftalate membranes has been studied.

The special peculiarities of the track-etched membranes are: high filtration efficiency, high uniformity of the specified pore diameters (±5%), the absence of particle generation by the membrane material, the smooth surface, durability and flexibility, resistance to cracking, biology inactivity. These membranes fit all demands on medical materials, and can be sterilized using any method.

Areas of Application

Membrane processes are broadly applied to water treatment in municipal service, food and pharmaceutical industries. Membrane technologies are widely used for the final stage of water treatment in the microelectronic and medicine.

Fig. 1 Track membrane with pore diametr 0.09±0.01 μm

Stage of Development

The methods of imobilization of biocidal substenses to cellulose, acetate cellulose, polysulfone, polyethylene-tereftalate membrane surfaces, methods of introducing biocidal polymers in membrane matrix and methods of formation of bactericidal membranes from polymer solution with introduced bactericidal components have been developed.

The optimum conditions for irradiation of the polymer PETF films with argon ions which were studied, and developed methods for physical and chemical treatment of the films and pore diagnostics in the total bulk of the track-etched membrane. Prepared samples of membranes for development of membranes with bacteriostatic properties for systems of water preparation

Contact Details

Anatoliy F. Burban, Head of Department of Chemistry, Ph.D., professor.
National University of Kiev-Mohyla Academy
Membrane Research Center
2, Skovoroda str., Kiev, 04070, Ukraine
Tel.(Fax) +38-044-425-3393
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Anatoliy P. Kobets, Ph.D., Senior Researcher
National Scientific Center “Kharkov Institute of Physics and Technology” Department of Heavy Ion Accelerator
1 Akademicheskaya St., Kharkov, 61108, Ukraine
Tel. +38-057-700-1539
Fax +38-057-700-3477
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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