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Home Biotechnologies Medical preparations (Medications)

Medical preparations (Medications)

Biosporin - a highly effective preparation on the basis of aerobic spore-forming bacteria for prophylactics and treatment of dysbacterioses, acute gastro-intestinal infections, purulent infections, a chronic stomatitis. Preparation Biosporin - combination of microorganisms which are characterized by high antagonistic activity to pathogenic and conditional pathogenic microorganisms and do not inhibit the normal microflora. The first domestic probiotic for human treatment Patented in Ukraine and Russia.

Test System «Elisa-Abebv-Strip» - is the first Ukrainian immunoenzyme test system for detection of the antibodies against Epstein-Bar virus in human serum for the diagnosis of diseases caused by the Epstein-Bar virus. Specificity and sensitivity rates of the test system are 100 % and 96 % respectively. An independent laboratory and clinical studies were conducted on the basis of State Epidemiological Station and a high efficiency assessment was obtained. The production samples of the test system «Elisa-Abebv-Strip-strip IgC» arc de veloped with the company «Diaproph-Med». Patented in Ukraine.

Subalin - a highly effective biopreparation, based on the recombinant strain of aerobic spore-forming bacteria capable lo produce human interferons. The preparation is effective towards to virus infectious agents, such as a flu, a herpes, a hepatitis, a meningoencephalitis and also has high antagonistic activity to a wide spectrum of pathogenic and conditional - pathogenic microorganisms. Combination of antibacterial and antivirus properties in one preparation - essentially new approach to treatment of many diseases mixed etiology. Patented in Ukraine and Russia.

 

Microcide - antibiotic medical preparation. Possess wide antibacterial spectrum against gram-positive, gram-negative and acid-resistant microorganisms. Preparation can be used for external treatment of different wounds, burns, frostbites, abscesses, ulcers; effective against purulent conjunctivitis, otitis, acute and chronic stomatitis, gingivitis, quinces, chronic cystitis, cervical erosion and other proinflammatory processes. Preparation promotes more rapid recovery of many diseases in comparing to other medicinal agents. State record of preparation

HUMAN SPECIFIC IMMUNOGLOBULINES

Immunoglobulines which contain the enhanced amount of specific IgG are active basis of preparations. The virus neutralizing action of antibodies as well as immunomodulating effect, influencing on the different links of the human immune system and enhancing nonspecific resistance of organism, increase their specific activity.

HUMAN IMMUNOCLOBULINE AGAINST A HERPES SIMPLEX VIRUS OF TYPE1 (Immunoglobulinum humanum contra herpes simplex virus typus 1) - preparation is applied for treatment of diseases, caused by herpes simplex virus i, namely: encephalitises, encephalomyelitis, meningo-encephalitises, arachno encephalitis, arachnoiditis, encephalo polyradiculoneuritis and others.

HUMAN IMMUNOCLOBULINE FOR HERPES SIMPLEX VIRUS OF TYPE2 TREATMENT (Immunoglobulinum humanum contra herpes simplex virus typus 2) - preparation for treatment of different diseases, caused by herpes simples virus of type 2 , namely primary and recuring urogenital infection of men and women, genital herpetic infection of pregnant women and obstetric pathology related with this.

ZOSTEVIR (Immunoglobulinum humanum contra Varicella Zosier virus) - preparation is applied for treatment of patients with a herpetic infection with the defeat of the nervous system which is caused by Varicella Zoster virus.

ANTICYTOMECALOVIRUS HUMAN IMMUNOGLOBULINE (Immunoglobulinum anticytomegalovirus humanum fluid) - preparation is applied for treatment of the clinical display of cytomegalovirus infections of adults and children, in particular: cytomegalovirus pregnant infections with the complicated obstetric anamnesis for prevention of failure of pregnancy (prevention of threat of miniaturing, development of fetoplacental insufficiency, prenatal foetus death); CMV-infections of unpregnant women with the complicated obstetric anamnesis for prevention of failure of planned pregnancy: primary CMV-infections of expectant mothers with non burden anamnesis for prevention of obstetric complications; CMV-infections in new-horn and children of junior age, which were horn by infected mothers and have clinical displays of disease; CMV-infections of adults arc with the defeat of central nerve system.

CITOBIOTECT (Immunoglobulinum anticytomegalovirus humanum fluid for intravenous introduction) Cytobiotect  applied for treatment of cytomegalovirus infection at patients with an immunosuppression after transplantations. Patients have therapy of sharp CMV-infection with an immunodeficiency, for example new-born, and also for patients with a medical immunosuppression or immunodeficiency, caused other reasons (including by AIDS).

HUMAN IMMUNOCLOBULINE AGAINST EPSTEIN-BARR VIRUS (Immunoglobulinum humanum contra Epstein-Barr virus) - preparation is applied for treatment of mononucleosis infectious and diseases of central and peripheral nervous system, caused by Epstein-Barr virus, including encephalitis, encephalomyelitis, meningo-encephalitis, arachnoencephalitis, arachnoidits and others.

GERPIMUN 6 (Immunoglobulinum humanum contra herpes virus typus 6 fluid) - preparation is applied for treatment of patients with a herpetic infection with the lesion of the nervous system caused by herpesvirus of type 6.

HUMAN IMMUNOGLOBULINE FOR CHLAMYDIA TRAHOMAIIS TREATMENT (Immunoglobulinum humanum antichlamidicum) - preparation is applied for diseases caused by Chlamydia trahomatis, namely, urogenital lesions including the salpingitis, urethritis, prostatism, cystitis, unmaturing of pregnancy, etc.

HUMAN IMMUNOGLOBILINE AGAINST TOXOPLASMA GONDII (Immunoglobulinum humanum contra Toxoplasma gondii) - preparation is applied for treatment of pregnant with toxoplasmosis and the obstetric pathology related with it, and also patients with the urogenital display on the toxopasmosis base.


Lectivir - preparation on basis of bacterial lectins for prophylaxis and treatment of influenza, herpes, hepatitis С and HIV/AIDS. Lectins possess unique specificity to different types of sialic acids and natural sialic acid-containing conjugates, can be used as analytical reagents to investigation and purification of glycoproteins, as molecular probes under analysis of surface cell structures. Patented in Ukraine.

Batumin is highly active antibiotic for treatment of staphylococcal infections on the basis of new compound - batumin, isolated from the bacterium of Pseudomonas genus. Antibiotic batumin has original chemical structure, and unique spectrum of antimicrobial action. The medication form - batumin ointment was developed for local treatment of staphylococcal infections. Patented in Ukraine.

Diastaph High selectivity of batumin towards Staphylococcus species has been used to develop a novel diagnostic preparation DIASTAPH (batumin impregnated disks containing 5 μg of antibiotic) ensured quick and reliable identification of microorganisms of Staphylococcus genus in pure and (in the urgent cases) in mixed cultures.

Beta-Carotene - the highly active natural antioxidant, biological stimulator and precursor of vitamin A. It is used to decrease the damages caused by reactive oxygen, phototoxic molecules and chemical radicals at radioactive influence and also to prevent and treat oncological and heart-vessel diseases. Beta-carotene stimulates cell regeneration processes and protects cell membranes (especially of liver cells), reduces skin and mucous membranes inflammation, increases the resistance of organism against infectious diseases, completely substitutes vitamin A and improves acuity of vision. Patented in Ukraine.

Polymyxin В - antibiotic of cyclopeptide origin for treatment infections caused by pathogenic gram-negative microorganisms Pseudomonas aeruginosa, Klebsiella pneumoniae. Salmonella and other bacteria resistant to antibiotics. Polymyxin В is also used for treatment patients with toxic shock state caused by mentioned bacteria and for preparative isolation of their toxins by complex formation. Polymyxin В is less toxic in comparison to the other polymyxins and therefore it can be used by intramuscular injection. The highly active, amucous and phage-resistant strains of Bacillus polymyxa were obtained by means of genetic selection and can be used in industry for polymyxin В production. The fermentation medium was optimized for maximal production of antibiotic during 72 hours of fermentation. The ratio between components B1, B2 and B3 in purified preparation of polymyxin В and its activity met the standards.

INTERFERON AND THEIR INDUCERS TO HPV INFECTION TREATMENT In the complex treatment of patients with papillomavirus-induced pretumor and tumor anogenital processes it is recommended to use the interferon medications and / or their inducers after treatment the related infectious-inflammatory diseases and also after a local cytostatic therapy and destructive interference. A new immunomodulating medications - interferon inducers have been proposed: fitor, flaraskin, fitomax, and also, with the JSC SIK «Diaproph-Med», the recombinant-interferon drug (diaferon) for the immunity correction. Patented in Ukraine.

Galactosoxidase - an enzyme for analytical detection of galactose and its derivatives in various biological materials. A producer of galactosoxidase has been isolated at the Institute, the enzyme production method has been developed. The basic advantages of the domestic preparation compared to foreign analogs are as follows: high specificity and lack of impurities of other enzymatic activity. The preparation is used in medical practice for the diagnosis of hereditary children disease of galactosemia, as well as in the research work.

Mycomelanin - new high-efficient preparation, isolated from biomass of melanin containing fungi. The preparation has radioprotective, antioxidant, detoxicant and antitumour properties. It can be used in medicine and food industry, and also in the production of high-purity substances.

Glucosooxidase - an enzyme of fungi origin. Its producer is Penicillium vitale Pidopl. et Bilai. Preparation is characterized by high antimicrobial activity, slows down growth of staphylococcuss and some pathogenic dermatophytes. Glucosooxidase is used in medicine as antimicrobial preparation with wide action spectrum for treatment of purulo-surgical diseases, in food industry, and also as a reagent for glucose determination in biological liquids.

Elastoterasa immobilised - alraline serine protease, which is a component of proteolytic complex producing by Bacillus subtilis. The enzyme may be used in medicine for healing of wounds at burns of III-IY degree, trophic ulcers, purulent wounds at first stage of process. Patented in Ukraine

Bacterial Lectins. The biotechnology of bacterial lectins production possesses unique specificity to different types of sialic acids and natural sialic acid containing conjugates. Producing lectins can be used as analytical reagents to investigation and purification of glycoproteins, as molecular probes under analysis of surface cell structures, and as perspective medicinal and prophylactic preparations against viral infections and immunodeficiencies of different etiology. Patented in Ukraine.

Landomycin E - the new antitumor polyketide antibiotic from angucyclines family synthesized by streptomyces. The antitumor activity of landomycin E was shown on the 60 lines of human cancer cells in the National cancer institute of USA (Bethesda). The leukemia cells were the most sensitive to this antibiotic. Landomycin E induced the typical process of programmed death (apoptosis) of cancer cells in the dose 1-7 μg/ml. The antibiotic also showed the same activity against multidrug resistant cancer cells, including doxorubicin resistant ones. Landomycin E possessed weak mutagenic activity and average cell toxicity. The biotechnology of landomycin E production was developed by means of fermentation of highly active strain Streptomyces globisporus 1912-3 in optimized conditions.

α-Calactosidase and α-N~Acetylgalactosaminidase. α-Calactosidase and α-N~Acetylgalactosaminidase of micromycete which are able to transform of erythrocytes III and II blood groups respectively to universal donor erythrocytes

Catalase (Еc I.Ii.I.6) from Penicillium vitale Pidopl. et Bilai. Characterized by high activity in the range pH4.0 - 9.0, thermo stability, resistance to H2O2. Fungi origin catalase retains activity in long-term storage (1 year). Catalase preparation used to remove excess of hydrogen peroxide, where it is used in technological processes or formed as an intermediate product. Efficient for animal blood lighting, bleaching furs, fabrics, in organic synthesis, nutrient media sterilization, and to obtaining of dosed amount of oxygen in the manufacture of some porous materials.

Cerbiden is natural highly effective preparation for dermatomycoses treatment. It has been obtained from medical plant of Asteraceae family. It is characterized with antifungal, antibacterial, anti-inflammatory and keratolytic action. The medical form - ointment-cerbiden is developed. Patented in Ukraine.

Contact Details

Organization: Institute of Microbiology and Virology named D.K. Zabolotny of the NASU
Address: 154, Acad. Zabolotnoho St., 03680, Kyiv, Ukraine
(+38044) 526-1179, Fax:(+38044) 526-2379
This e-mail address is being protected from spambots. You need JavaScript enabled to view it , This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Web: http://www.imv.kiev.ua

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