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Home Moldova Technologies Izofural - New Antiseptic

Izofural - New Antiseptic

Description

Izohidrafural - new organic substance of the nitrifurane group; shows evidencеd antibacterial activity to a large spectrum of gram-positive and gram-negative microorganisms.

IZOFURAL – new antibacterial remedy, developed on base of this organic compound, with low toxicity and strong bactericide activity against the wide spectrum of the gram-positive and gram-negative microorganisms.

Innovative Aspect and Main Advantages

It is 4 times more active and 9 times less toxic then furatsilin (fig 1). Synthesis procedure is simple, some of the synthesis’ components are approachable from local raw materials. The mode of production and keeping conditions are simple. The preparation is clinically and ecologically safe and has high stability (~ 5 years).

Areas of Application

Medicine, veterinary, pharmaceutical industry. The drug IZOFURAL is effectively used in treatment of osteomyelitis, burns.


Fig. 1 Toxicity and bactericidal activity of Izofural.


Before treatment


After 5 days of treatment

Fig.2. Results of Izofural treatment (patient B., 47 years; Politraumatism of open fracture of left calf).

Stage of Development

Active pharmaceutical ingredients and the preparation have been pre-clinically tested in laboratory conditions (for antibacterial activity, stability in prolonged storage conditions and autoclave, dermatoirritative action, carcinogenic action, embryotoxicity, impacts on immunity and therapeutics).

It has been initiated clinical trials of preparation.

Covered by Patent of Moldova, Nr 196.

Contact Details

State University of Medicine and Pharmacy “N.Testemitanu”
Contact person: Prof. Viorel Prisacari
Address: Bd. Stefan cel Mare 165 Chisinau МD 2004, Republic of Moldova
Tel.: (+ 373 22) 44 630; 41 782
Fax: (+373 22) 42 344
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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