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Home Moldova Technologies New Antibacterial Substances with Antibacterial Activity to a Large Spectrum of Gram-Positive and Gram-Negative Microorganisms

New Antibacterial Substances with Antibacterial Activity to a Large Spectrum of Gram-Positive and Gram-Negative Microorganisms

Description

The invention relates to new group of organic compounds, biologically active, from tiosemicarbazone class with low toxicity and evidenced bactericide activity to a large spectrum of gram-positive and gram-negative microorganisms.

Innovative Aspect and Main Advantages

The presented compounds being of about 2 – 64 times more active to the gram-positive and gram-negative bacteria, than the prototype (furacilinum). The toxicity of the presented compounds is > 1500 mg/kg and belongs to the class of compounds with low toxicity.

Areas of Application

Medicine, veterinary, pharmaceutical industry.


Fig. 1 Bactericidal activity of the new organic compounds.

Stage of Development

Compounds have been tested for antibacterial and antifungal activities in laboratory conditions. Covered by Patent of Moldova, Nr 2942.

Contact Details

State University of Medicine and Pharmacy “N.Testemitanu”
Contact person: Prof. Viorel Prisacari
Address: Bd. Stefan cel Mare 165 Chisinau МD 2004, Republic of Moldova
Tel.: (+ 373 22) 44 630; 41 782
Fax: (+373 22) 42 344
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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