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Home     Ukrainian Institutes Institute for Problems of Cryobiology and Cryomedicine, NASU

Institute for the Problems of Cryobiology and Cryomedicine, NASU

Logo of Institute for Problems of Cryobiology and Cryomedicine, NASU

General Information

The Institute for the Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine was formed in 1972 by combining two existing organizations:

  • The Institute of Low Temperature Physics and Engineering (USSR Academy of Sciences).
  • Laboratory for the Low-Temperature Preservation of Bone Marrow and Blood (Kharkiv Institute for the Advanced Training of Physicians).

The Institute is a unique and comprehensive research and development institution which effectively combines the experience and efforts of 326 technical staff, including one Academician (Director of the Institute, Dr. Goltsev A. M.), 19 Doctors of Science, 116 Candidates of Science (Ph.D.), and 47 Scientific Collaborators comprising physicists, biophysicists, chemists, biochemists, mathematicians, biologists, and medical specialists. Institute science departments are crybiophysics, biochemistry of cold adaptation, cryophysiology, cell cryophysiology, crybiology of reproductive preservation, low temperature systems, cryobiochemistry and pharmacology of neurohumoral systems, experimental cryomedicine, cryoimmunology, cryopatophysiology, cryomorphology, cryocytology, cryoprotectants, cryobiochemistry, long-term storage of biological specimens at low temperatures, low-temperature repository of diological specimens.

Major research areas of the Institute

  • Methodological investigations of cryoinjuries, cryoprotection, the natural integrity of biological objects exposed to low-temperature conditions and their subsequent recovery;
  • Development of methods for the cryoprotection of biological systems at various organizational levels, and on this basis the development of cryopreservation techniques for biological entities and the means for their implementation;
  • Utilization of hypothermal conditions, cryotherapy and the cryopreservation of biological entities to treat various diseases;
  • Cell and tissue transplantation.

Fundamental scientific research at the Institute has yielded significant results that are unique in the scientific world. In particular, Institute facilities are used to treat such medical conditions as hematopoiesis aplasia, various forms of leukosis, malignant tumors, diabetes, infertility, and others. Highly efficient methods for the artificial cooling of a human being with the goal of regulating the level of functional activities of various organ systems to promote recovery from alcohol addiction, poisoning, vegeto-vascular dysfunctions and other diseases have been developed.

Preparations for presowing processing of seeds
Preparations for presowing
processing of seeds

Academician V.Grishenko in one of the Institute’s laboratories
Academician V.Grishenko in one
of the Institute’s laboratories

Low-temperature bank of biological objects.
Low-temperature bank of
biological objects.

List of technologies developed at the Institute

A partial list of technologies developed at the Institute that are on the verge of being introduced or implemented in wider, practical applications includes:

  • cryopreservation of sperm and embryos of fish, birds, mammals;
  • ultra-rapid freezing of sperm, embryos of humans and animals;
  • cryopreservation and liophylization of microorganisms of various taxonomic groups (yeast, actinomyces, lactobacilli, cyanobacteria, bifidobacteria) for use in the food industry as well as in the medical and veterinary fields;
  • long-term storage of various biological entities and specimens (human tissues and organs, rare and endangered animal species and plants) on the basis of an automated cryobank system;
  • treatment of seeds prior to sowing to increase resistance to extreme factors.

Scientific Cooperation and Technology Transfer

In recent years the Institute for the Problems of Cryobiology and Cryomedicine has been awarded 170 patents, 236 authorships of record, and published 77 manuscripts, with a total publication volume of over 2,700 articles. The Institute as a whole and its scientists as individuals have won numerous Soviet and Ukrainian scientific awards and grants, and the Institute maintains close contacts with cryobiological centers in the United States, Great Britain, Germany, India, Czech Republic, Slovakia, Bulgaria, Belgium, Netherlands, Israel, Spain, France, and Sweden. Nonetheless, the Institute is very interested in improving and expanding its capabilities, and of course is equally interested in contributing to fundamental scientific and medical cryobiological research and development throughout the world. The Institute enthusiastically welcomes foreign collaborators and inquiries for initiating cooperative efforts.

Contact Details

Goltsev A. M., Director, Academician of NASU
Address: 23, Pereyaslavskaya str., Kharkov, Ukraine 61015
Tel.:+380 57 373-4143
Fax: +380 57 373 3084
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


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