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Home Uzbekistan Technologies Synthesis of New Derivatives of N,N-Diethylhydrazine

Synthesis of New Derivatives of N,N-Diethylhydrazine

Description

The reactions of N,N-diethyl-hydrazine with halogenated alkyl substances, carboxylic acids and their anhydrides have been studied and the possibilities of using novel obtained derivatives of N,N,-diethylhydrazine in agriculture and medicine have been determined.

Innovative Aspect and Main Advantages

There have been investigated bacteriostatic activities of the obtained substances, and there have been shown the positive effect on their use as medicines against gummosis and “root rotting” of cotton-plant, as well as on growth and productivity (yield) of vegetable species.

Areas of Application

Medicine, agriculture, organic synthesis.

I

X=-I, R=-CH3 (a), -C2H5 (b),
-C3H7 (с), -C4H9 (d);
X=-Br, R=-C2H5 (e),
-C3H7 (f), -C4H9 (g);
X=-Cl, R= -CH2C6H5 (h)

II

R= -H(a), -COOH(b), -CH2OH(c),
2-NO2-C6H4-(d), 3-NO2C6H4-(e),
4-NO2-C6H4-(f), 3-HO-C6H4-(g),
4-HO-C6H4-(h), 4-NH2-C6H4-(i),
2-C6H5-CO-C6H4-(j)

III

Fig. 1. The structures of the obtained substances.

Stage of Development

  • Laboratory tested.
  • Complex biological activity of new derivatives of N,N-diethylhydrazine has been studied.
  • Toxicity study of more effective derivatives of N,N-diethylhydrazine has been carried out.

Contact Details

National University of Uzbekistan, Chemical Department
Contact person: Prof. A.K.Tashmukhamedova
Address: Vuzgorodok 100174 Tashkent, Uzbekistan
Tel.: (998 71) 246 6358
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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